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Visible Spectrophotometric Determination of Itopride Hydrochloride in Pharmaceutical Formulations

C. Shechinah Felice, K. Srinivasulu, V. Praveen Kumar and S. Vijaya Saradhi

A simple, sensitive, precise, accurate reliable and reproducible spectrophotometric method has been developed for the determination of itopride hydrochloride in pharmaceutical formulations. This method is based on the formation of colored species on binding of itopride hydrochloride with sodium carbonate, NaOH followed by F/C to produce blue colored chromogen (4max at 520 nm). Results of analysis were validated statistically and by recovery studies. This method is successfully employed for the determination of itopride hydrochloride in various pharmaceutical preparations.