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Synthesis, Physical Characterization and Antibacterial Activity of Some Derivatives of 2-Amino Benzothiazoles

Shipra Baluja, Sumitra Chanda and Anchal Kulshrestha

Some novel Schiff bases and thiazolidinones are synthesized from 6-methoxy 2-amino benzothiazole and their characterization was done using IR, NMR and mass spectral data. The antimicrobial screening of these synthesized compounds were done in two polar solvents DMF and DMSO. A differential effect of the compounds in a particular solvent (DMF / DMSO) inhibited different strain to a different level. This suggests that anti-microbial activity depends on molecular structure of the compound, solvent used and the strain under consideration.