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Synthesis of new 2-propenoylamides and 3-H-quinazolin-4-one derivatives

S.A.Shiba, A.K.El-Ziaty, N.K.El-Aasar, H.A.Al-Saman

A series of novel quinazolinones, pyrazolo [5, 1-b] quinazolines, beside acrylonitrile derivativeswere synthesized by reaction of 3,1-benzoxazinone (1) and 4- chloroquinazoline (8) with different nitrogen nucleophiles. The structures of all novel compounds were identified by correct elemental and physical analysis.