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Synthesis, Characterization and Biological Screening of Some 3,4,5-Substituted 1,2,4- Triazole

J. W. Dhore and G. D. Thorat

Condensation of substituted 1,3,4-oxadiazoles and isoniazide gives N-((3,5-substituted)-4H-1,2,4-triazole-4yl) isonicotinamide(D1-4). The IR, 1H NMR, and nitrogen analysis characterized all these compounds. The newly synthesized compounds were screened for antibacterial and antifungal activity.