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Sol-gel chemistry is used to create an organic-inorganic hybrid with short organic molecular chains.

Lara Wilson

With KH550 and KH560, an oligomer with short organic molecular chains was successfully created. By using sol-gel chemistry, this oligomer was coupled with calcium chloride, tetraethyl orthosilicate, and other ingredients to create an organic-inorganic hybrid biological material (OI-BM). A number of instrumental characterizations, such as nuclear magnetic resonance spectrometry, scanning and transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray energy spectroscopy, and inductively coupled plasma spectrometry, were used to completely describe the hybrid. Under compression, OI-BM demonstrated elastic deformation. The strain at failure and modulus of toughness of OI-BM were approximately 4.5 times and 4 times greater than those of 45S5 bioactive glass (45S5-BG), although the elastic modulus and ultimate stress of OI-BM were 0.4 0.1 GPa and 23.0 4.0 MPa, respectively, lower than those of 45S5-BG. Due to the enhanced mechanical qualities, the hybrid is simple to produce, indicating great machining properties. Due of its strong bioactivity, the hybrid OI-BM formed hydroxyapatite in simulated bodily fluid in 1 hour. The hybrid's favourable cytocompatibility was further shown by the CCK-8 experiment. As a result, the hybrid may be a material option for an implant that meets the mechanical property requirements.