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Potential Of Developed Microbial Biofilms In Generating Bioactive Compounds

Gamini Seneviratne, Junaida Shezmin Zavahir

Thus far, only monocultures and mixed cultures have been used to generate bioactive compounds. Here, bioactive compound production of a developed penicillium spp.-bradyrhizobium elkanii SEMIA 5019 biofilm was compared with monocultures of the two microorganisms. The biofilm was observed to generate a higher number of detectable compounds with relatively high concentrations in comparison to the bacterial and fungal monocultures. This technology can be used to produce different compounds for the discovery of novel compounds that can be used in drug discovery studies, with applications to many fields of biotechnology.