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Mild and efficient copper sulphate catalyzed synthesis of bis-indolylmethanes

Uttam B.More, Bapurao S.Sonawane, Pramod P.Mahulikar

A mild and efficient electrophilic substitution reaction of indole with various aldehydes and ketones in presence of copper sulphate as catalyst, afforded bis-indolylmethanes in good yields. The simple isolation of product is additional feature of the methodology.