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Formulation and Evaluation of Roxatidine Floating Tablets

P. Chandrawanshi, H. C. Patidar, P. Pandey and R. Kapadia

Floating tablets are the systems, which are retained in the stomach for a longer period of time and thereby improve the bioavailability of drugs. Roxatidine is an anti-ulcer drug; having bio-availability 80-90% and protein binding 5-7%. The purpose of present investigation was to prepare formulation and evaluate the floating tablets of roxatidine. The floating tablets were evaluated for uniformity of weight, hardness, friability, drug content etc.