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ELECTROCHEMICAL DETECTION OF SOME WATER SOLUBLE AND FAT SOLUBLE VITAMINS BY USING BARE PENCIL GRAPHITE ELECTRODE

Tolga Saruhan, Perihan Adun, �?°hsan Erol �?�?z�?§il

Vitamins are a group of organic compounds needed in small quantities by the body to perform its essential functions like growing, regulating metabolism and maintain a healthy immune system. In recent years, substantial efforts have been focused on development of simplified, fast and cost-effective approaches for vitamin analysis. Aim of this study was electrochemical detection of some water and fat-soluble vitamins individually and simultaneously by using bare Pencil Graphite Electrode (PGE). Vitamins of C, B1, B6, B12, A, D3, and E were selected and electrochemically analyzed in pharmaceutical perpetrates. Simultaneous analysis of water-soluble vitamins by using DPV with PGE can be promising technique for the determination of vitamin C and B6 or vitamin B1, B12 and B6. In the case of fat-soluble vitamins, resolution between vitamin D3 and E was not satisfactory. However, vitamin A and D or vitamin A and E could be detected in a single run. Limit of detection of the selected vitamins were quite low (4-548 µg/ml).