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Development of a novel serotonin sensor based on Na-montmorillonite nanoparticles modified carbon paste electrode

Qiong He, Dongyun Zheng, Shengshui Hu

ANa-montmorillonite nanoparticlesmodified carbon paste electrode (CPE) denoted as serotonin sensor is described.Amixture of fine graphite powder and Na-montmorillonite nanoparticles is obtained by dispersing in paraffine, and it is applied for the preparation of serotonin sensor. The electrocatalytic oxidation of serotonin atNa-montmorillonite nanoparticles modified electrode is examined by using cyclic voltammetry (CV). The mechanismof electrochemical behavior of serotonin onNa-montmorillonite nanoparticles film electrode is investigated. The oxidation peak current linearly increased with the serotonin concentration in the range of 0.45 ìM to 51 ìM with a low detection limit of 57 nM. This Na-montmorillonite nanoparticles modified electrode shows high sensetivity for the determination of serotonin. It has been used to monitor serotonin in human blood serum as a sensor.