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Antagonistic potential of Coriolopsis species extracts on Escherichia coli isolated from well water in Akure, Nigeria

V.O.Oyetayo, M.U.Oghumah

The current study evaluates the inhibitory effect of extracts of Coriolopsis sp., a wild macro fungus, on E. coli obtained from well water. A total of fifty well water samples were collected from different parts of Akure metropolis in SouthWest, Nigeria. Fifteen of the samples were positive for Escherichia coli. Ethanolic extract obtained from Coriolopsis sp (CET) displayed a significant inhibitory effect on E. coli from well water at concentration of 100mg/ml. The zones of inhibition range between 1.5 to 13mm. However, ethyl acetate and petroleum extracts (CEAand CPE) do no showany inhibitory effect at concentrations of 12.5mg/ml to 100mg/ml. Fractions obtained fromCET were able to inhibit the growth of E. coliwith zones of inhibition in the range of 12 to 27mm. The study revealed that extracts of Coriolopsis species contains bioactive compounds that can serve as alternative in combating multi-drug resistant E.coli.