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An efficient microwave assisted synthesis of novel pyrimidine-5-carboxamides

Haresh Ram, Dipti Dodiya, Kishor Ahir, Amit Trivedi, Viresh Shah

Synthesis of a series of pyrimidines (4a-j) was achieved from different acetoacetamides, 4-(2,4-dinitrophenoxy)phenyl aldehyde and urea using microwave irradiation within 5-10 min. with high yields. The structures of the products were supported by FT-IR, PMR and mass spectral data.